Director Clinical Pharmacology amp Pharmacometrics

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Clinical Pharmacology & Pharmacometrics plays a key role in the drug development process such that we plan, design and execute clinical pharmacology studies while maximizing the potential for model-based drug development to drive decisions that inform the course of the clinical development program. This group focuses on 4 therapeutic areas including Immunology, Cardiovascular, Fibrosis, and Neuroscience.

Job Description

The vision for Directors in the group is to be able to function in a blended role that includes both classical clinical pharmacology skillsets combined with quantitative analysis skills. Given the breadth of the portfolio, Directors in this group would have the opportunity to serve as the clinical pharmacology & pharmacometrics leader on compounds in both early and late stages of development as well as assets that are small and large molecules. Based on the person’s interest and capabilities, there would be opportunities to stretch beyond one therapeutic area and work on an array of molecules. BMS is committed to people development and we foster a learning environment to build scientific and leadership skills. In addition to scientific projects, scientists will also be able to participate in and lead company initiatives and scientific forums. We are seeking someone who is passionate to develop medicines that help patients and experienced in clinical pharmacology & pharmacometrics who expresses strong communication skills to be able to build strong relationships with cross-functional members as well as be able to lead within a matrix team.

Job Responsibilities

Contribute to the development of compounds developed across multiple therapeutic areas including but not limited to immunology, cardiovascular, virology, fibrosis, and oncology

Responsible for the creation of CP&P development plans that is aligned with compound strategy and execution of clinical pharmacology deliverables outlined by the development teams

Lead / Contribute to the design of clinical studies to characterize the pharmacokinetic, pharmacodynamic, and drug metabolism properties, as well as analyze, interpret and report data from such studies

Provide strategic input into the design of Phase 2/3 clinical studies and world-wide registrational strategy in line with the CP&P strategy for the compound

Plan, execute, and report on model-based pharmacokinetic and exposure-response analyses of data from clinical studies

Represent the CP&P function on cross-functional drug development teams, contribute to design drug development strategies, regulatory submissions, and participate in interactions with health authorities

Lead and participate in departmental initiatives and represent CP&P on cross-functional initiatives / workstreams / taskforces

Work with Business Development teams and provide critical expertise to assess external acquisitions

Supervise and mentor a group of CP&P scientists, if needed

Manage and provide mentorship and guidance to staff and CP&P function

Independently serve as the CP&P lead for one or more assets in the BMS drug development program

Required Qualifications

A PharmD with post-doctoral training or PhD in pharmaceutical sciences, pharmacology, biomedical engineering, or a related field

7 years of experience in clinical pharmacology and pharmacometrics, including experience in characterizing the pharmacokinetic and pharmacodynamic (biomarker/safety/efficacy) properties of small molecule and biologics drugs

In-depth knowledge of current practices and issues in clinical pharmacology and pharmacometrics

Strong written and oral communication skills necessary to report on and deliver scientific presentations

Demonstrate the ability to work in a dynamic team oriented environment

Preferred Qualifications

Experience with the following software is highly desired: R, NONMEM, MONOLIX, and WinNonlin

Travel Required

Local and international travel for conferences and regulatory meetings may be required depending on project needs up to 5-10% of the time

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Company info

Bristol-Myers Squibb Company
Website : http://www.bms.com