Veterinary Care and Training Manager - Vivarium

Profile

Who We Are From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases.For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics and molecular biology, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more. And the more people we reach, the more our impact can grow. We transform lives through genetic discovery. Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard \u2013 so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients. BioMarin\u2019s Research & Development group is responsible for everything from research and discovery to post-market clinical development. Research & Development involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class or best-in-class therapeutics that provide meaningful advances to patients. Come join our team and make a meaningful impact on patients\u2019 lives. We are seeking a motivated Veterinary Scientist (actual level depends on experience) to join the BioMarin Animal Resources (Vivarium) Group to assist in managing the veterinary program for animal care, animal program training, and assist the Attending Veterinarian in program development. This position is critical to regulatory compliance for BioMarin\u2019s Animal Care and Use Program. This role reports into the Attending Veterinarian.\u00A0 The successful candidate will advise research staff on proper veterinary care, specifically pain/distress management and peri-operative care. Collaborate with faculty on research projects including design and performance of animal models, as well as methods and techniques. Review IACUC protocols and participate in semiannual IACUC inspections and other veterinary related IACUC responsibilities. Assist in the review of all animal use protocols and institutional programs involving animals in research, testing and teaching. The successful candidate will have a dynamic role in Veterinary Care & Training and will be responsible for clinical care of research animals (treatment of illnesses, pain and distress management, and surgical consultation), preventative and diagnostic medicine programs (quarantine, animal biosecurity, and surveillance), surgery, investigator and technician training, compliance support (protocol review, IACUC, post-approval monitoring), interaction with inspectors, participation in program description documentation, and collaborative research with investigators. The successful candidate will also assist in in-vivo study activities for various therapeutic indications, including dosing of test article in rodents, tissue collection, and sample management.\u00A0 The ideal candidate will have extensive Biotech/Pharma industry in-vivo experience (proficient in in vivo technical tasks with rodents including (IV, PO, SC, IM, IP dosing) and familiarity with genetically engineered mutant rodent disease models. Experience in breeding colony management and familiarity with mouse model creation processes and techniques (e.g. CRISPR, Cre-lox and Tet-on systems, mouse IVF concepts) and familiarity with mutant model types (transgenic, knockout and knock-in models, conditional and traditional mutant lines) is highly desired. Additionally, proficiency in in-vivo methods such as administration of test articles, perfusion and tissue collection, blood collection, as well as rodent surgical models is preferred. Candidate level at hire will depend on education and experience. Responsibilities: Veterinary Care:Provide routine care under the supervision of the Attending Veterinarian including on-call schedule to provide after-hours and weekend coverage.Experience with USDA regulated species - Perform and document physical examinations, preventative care, and experimental collections for incoming and existing animals (Guinea Pigs and Rabbits)Oversee the program of acclimation and/or quarantine of incoming animals. This includes all necessary and appropriate health checks and surveillance of incoming and resident animals, including release of animals from acclimation/quarantine.Oversee or facilitate (depending on level) under supervision of the Attending Veterinarian a program of preventative and diagnostic veterinary care; Supervise or perform diagnostic procedures and processing in house or with service providers (includes fecal analysis, gross necropsy, diagnostic imaging, and rodent sentinel health surveillance).Provide oversight and training for new and existing employees to assure quality care is provided to the animals by staff and scientists.Provide orientation for staff, scientists, and other personnel prior to assigning independent vivarium access.Assure compliance with all internal and external regulatory and accreditation requirements which includes service on the qualified vendor and external study CRO audit committee.Maintain records to comply with applicable local, state, federal regulations, applicable animal welfare accreditation standards, and internal compliance regulations.Other duties as assignedTraining:Provide training on routine in vivo techniques for existing and new investigators and vivarium staff including injection (IV, PO, SC, IM, IP, etc.) and bleeding techniques (tail bleed, saphenous, submental, etc.).Assist in IACUC process for Post approval monitoring quality assurance and establishment of animal care and facility policies and proceduresProvide training to vivarium and research staff in surgical and non-surgical procedures including but not limited to anesthesia administration, monitoring and recovery, aseptic technique, surgical and non-surgical procedures, euthanasia and tissue collectionOther duties as assignedGeneral requirements for the position:Strong analytical, problem-solving, and decision-making skillsStrong understanding of genetically engineered models, breeding, and management and Gene therapy modalitiesExcellent oral and written communication skillsMust be able to utilize computer databases for data entry and point of care observationsMust be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teamsMust be able to regularly read, understand, verify accuracy, and document various written of protocols, including Animal Care and Use Protocols and Standard Operating ProceduresMust be able to work with external regulatory agencies and accreditation groups.Maintain and oversee a comprehensive animal biosecurity program including procedures for quarantine, health surveillance, environmental monitoring, internal animal movement as well as animal imports and exports.Participate in IACUC and USDA inspections, as well as AAALAC site visitsSome \u201Coff-core business hours\u201D work required.Complete all company training requirements.Perform all work per designated safety standards.Maintain registered certifications and licenses as applicable.\u00A0 For licensed DVM, must gain licensure within 1 year for California.Comply with Personal Protective Equipment requirements and occupational health to perform work tasks.Performs other duties as assigned.This position is an on-site critical required position Other duties as assignedEducation and Experience Requirements:\u202F(Preferred) DVM degree from AVMA accredited institution, Licensure to practice veterinary medicine in at least one U.S. state,\u00A0USDA certification preferred,\u00A0ACLAM/ECLAM Board Certified or eligible preferred, or 2 years\u2019 experience in Biotech/PharmaRVT candidates, graduated from an accredited veterinary technical program or equivalent MS degree in Animal or Veterinary sciences program, must have experience in Biotech/Pharma in vivo animal program (6 years), foreign DVM equivalent to RVT,\u00A0Must have at a minimum ALAT AALAS certificationPhD in biology/animal/veterinary science, and experience in Biotech/Pharma in vivo animal program role (4 years),\u00A0Must have a minimum ALAT AALAS CertificationHighly qualified BS candidates may also be considered, must have degree in biology/animal/veterinary science, must have extensive experience in Biotech/Pharma animal program care and use (8 years),\u00A0Must have at a minimum LATG AALAS certification PLEASE NOTE: Absent a Medical or Religious reason that prohibits vaccinations, all our incoming employees must be vaccinated for COVID-19. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, sexual orientation, national origin, disability status, protected veteran status, or any other characteristic protected by law.

Company info

BioMarin Pharmaceutical Inc.
Website : http://www.biomarin.com